Targeted ultrasound-guided biopsy is performed when the lesion is visible on ultrasound. Which statement is true?

• A. It uses real-time ultrasound to guide the needle into the lesion identified on ultrasound
• B. It uses MRI to guide the needle
• C. It samples non-targeted tissue
• D. It is used when the lesion is not seen on ultrasound

Answer: (A)

Targeted ultrasound-guided biopsy relies on seeing the lesion with ultrasound and using real-time imaging to steer the biopsy needle into that exact area. The live ultrasound view lets the operator watch the needle as it advances, adjust its path, and ensure the sample comes from the lesion identified on ultrasound while avoiding surrounding structures. This is why the statement is true: the technique uses real-time ultrasound to guide needle placement into the ultrasound-visible lesion. It’s not MRI-guided, it’s not for non-targeted sampling, and it isn’t performed when the lesion isn’t seen on ultrasound. If the lesion isn’t visible, alternative imaging-guided biopsies (like MRI- or CT-guided) would be considered.